Kenta Biotech includes first patient in its first-in-human trial of KBSA301

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15.06.2012

Kenta Biotech today announced an important step towards a more efficient treatment of hospital infections: The first patient was enrolled in the phase I/II clinical trial with KBSA301, a fully human antibody for the treatment of severe pneumonia caused by Staphylococcus aureus (S. aureus).

In this clinical trial, 44 patients suffering from severe pneumonia caused by S. aureus admitted in intensive care units around Europe will be administered a single dose of KBSA301, or placebo, in addition to standard antibiotic therapy. KBSA301 is developed by Kenta Biotech as a new treatment option to fight severe S. aureus infections, including those caused by antibiotic resistant strains. Founded six years ago, Swiss biotech start-up Kenta today is a leader in the field of antibody treatment in nosocomial infections.

The fully human monoclonal antibody KBSA301 was identified by using Kenta Biotech’s proprietary MabIgX® technology. In the field of infectious diseases, this is one of the few therapeutic monoclonal antibodies that is tested in a first-in-human trial directly in patients. Kenta Biotech, in this way, can accelerate the clinical development and bringing this new compound faster to patients.

Franco Merckling, CEO said: ”This is a great day for patients, for doctors and for Kenta Biotech. Thanks to intensive research and the dedication of our outstanding staff, we are able to bring a human monoclonal antibody with an innovative mode of action into clinical development in record time. I am confident that this trial will deliver promising data and pave the way for change in the treatment of severe S. aureus pneumonia.”

Kenta Biotech is a biopharmaceutical company headquartered in Zurich-Schlieren, Switzerland, focused on the development of innovative fully human monoclonal antibodies for the prevention and treatment of life-threatening infections. Kenta Biotech‘s lead-product, Panobacumab (KBPA101) has successfully completed a phase IIa proof-of-concept trial.

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